One of the main characteristics of an isolator system is its capability to be bio-decontaminated toxic environment and to keep a germ-free environment whatever operation or transfer performed. Even, in some application, the isolator is biodecontaminated after process, in order to eliminate potential biohazard.

Decontamination of toxic environment is performed by contact of a gas or vapor form sterilant, generated by a stand-alone or integrated device. La Calhène has experience with several suppliers.

All isolators for aseptic and bio-hazard operation are equipped with connections and control for either bio-decontamination of toxic enviroment device selected.

La Calhène has participated to the development and integration of multiple bio-decontamination systems. Some have been developed for specific applications, like bio-decontamination with optimized cycles of large filling isolator suites.